THIEVES broke into the British Heart Foundation shop in Grantham High Street, making off with the contents of the safe and the till.
Just days after Granthamians raised thousands for the charity taking part in the Santa Run, thieves broke into the store before making off with cash and items donated to charity by Grantham people.
They are believed to have got inside via the roof.
Lincolnshire Police spokesman James Newall said: “This is extremely upsetting for the staff at the shop.
“The cash which has been stolen was intended to help a good cause.
“We are appealing for anyone with any information at all to call us as soon as possible to help us with our inquiries.”
The charity estimates the total cost to the British Heart Foundation through the damage caused and the cash and stock stolen is more than £500.
Linda Puchala, the British Heart Foundation area manager, is asking people to come forward with any information on the break in, as well as asking people to help by donating more items.
She said: “We absolutely rely on the support of the Grantham community to keep us running and without their vital donations we risk reducing the care and support to heart patients across the county.”
Police believe the burglars got inside the store after climbing onto the roof last Thursday night (December 8) and cutting through the felt.
They then got inside the shop through the attic.
The thieves broke into the safe, stealing £80, and also stole money from a till after forcing it open.
Among other items taken was some jewellery.
Anyone with any information on the burglary is asked to call Lincolnshire Police or call independent charity Crimestoppers anonymously on 0800 555 111.